Biyernes, Agosto 10, 2012

Hormone Replacement Therapy: Do the Risks Outweigh the Benefits?Hormone Replacement Therapy: Do the Risks Outweigh the Benefits?

2012.

A year full of innovations, inventions, and advancements in technology.

A year full of possibilities and potential development.

The year 2000s introduced a lot of concepts, things, and thoughts to the world. One of these things is the introduction of Hormone Replacement Therapy.

Nowadays, people sometimes take things lightly. For example:
                         A student sees a candy wrapper in the hallway, and instead of picking it up, he shrugs and says "Its just one tiny piece of candy wrapper, it couldn't clog a drainage system." Or;
                         A ten year old boy was urged to smoke and instead of refusing, he complies and says, "Its just a stick, I wont do this again. Ngayon lang naman 'to  (Its just this once)." Or;
                         A woman was discouraged by a doctor to do a certain procedure and instead of following the doctor's advice, she goes to another clinic and undergoes through the procedure, saying "Its just one little medical procedure. It wouldn't hurt. Medical procedures aren't supposed to hurt people, they're supposed to help them."

These situations occur repeatedly and never seem to cease. What we do not know is when different tiny pieces of candy wrapper would come together and clog a drainage system, causing flood; or when a stick of cigarette a day, for a year, would never end and thus becomes a habit; or when a little medical procedure would not have gone the way that you've planned and thus, endangers your life.

Let us take Hormone Replacement Therapy into the picture.

Although Hormone Replacement Therapy (HRT) can decrease the risk of developing fractures, it increases the risk of developing certain cancers, thromboembolic events, and urinary incontinence, according to a review published online on May 29, 2012, in the Annals of Internal Medicine.

The authors of the review looked at studies of 2 types of HRT therapy -- estrogen-plus-progestin therapy and progestin-only therapy -- published since the release of the USPSTF's initial recommendations in 2002.  Prior to 2002, HRT was used to prevent chronic conditions, including cardiovascular disease, dementia, and osteoporosis. However, as a result of associating HRT with adverse effects, the therapy is currently indicated only for prevention of osteoporosis and for short-term treatment of menopausal symptoms.

The authors report that the benefits of HRT include fewer fractures and fewer cases of diabetes, but also that HRT is associated with higher risks of certain conditions. Patients who received either kind of HRT had more cases of stroke, gallbladder disease and urinary incontinence. Those who received estrogen-plus-progestin also had more cases of invasive breast cancer, deep venous thrombosis, pulmonary embolism, probable dementia and death from lung cancer.

HRT patients also had more abnormal mammography results, larger tumors, and more advanced stages of breast cancer. other cancers such as lung, endometrial, ovarian and cervical cancers, were not increased during the estrogen-plus-progestin trial, although the incidence of death due to lung cancer was increased to those taking estrogen plus progestin.

And so, regarding HRT, do the risks outweigh it benefits?

....

As Pharmacy students, these matters should be subject to our attention and time. As a future part of the Health Care Team, we should at least be concerned with the matters that involve us, the community or the public and the medical and health care field.

....

One last thought, have you ever heard the saying "Big Things come from small things" ??
Believe it. Its true. :')

....

Take care everyone :p

....

4 (na) komento: